Q: Can I Get my Label on your Skincare Sample Sets? MVP Selections offers Ancient Minerals® Magnesium Oil Sensitive, a special formula for sensitive skin. Make sure it is mixed well and not lumps are present. Allantoin. Allantoin is a colorless crystalline powder that is soluble in water at approximately 0.6%. "Allantoin is right up there next to the cica and madecassoside trends — all are skin-soothing, skin-calming ingredients used for sensitive skin-friendly products," she explains. Description : Allantoin works as an anti-irritant. 7. 6. In a separate container, mix together rosehip seed oil and CoQ10 Powder. Today, allantoin is prized for its ability to cleanse the kidneys. Allantoin is stable in the pH range 3-8 and to 80°C prolonged heating. If allantoin is not soluble in oil (according to PubChem ) then how is it this person was able to incorporate it into this anhydrous cream with no grittiness or bumps? Allantoin encourages new and healthy … Identification Test. Is allantoin really not oil soluble? Allure Korea editors and K-beauty experts alike have also been loving Dermatory's line that specifically spotlights it with allantoin-infused moisturizers, toners, and masks. Allure may earn a portion of sales from products that are purchased through our site as part of our Affiliate Partnerships with retailers. Hand mixer or other high shear mixer, Orange Blossom Distillate        41.37%                  .0414, Deionized Water                         41.37%                  .0414, DMAE                                           5.2%                      .0052, OptiMSM                                     5.2%                      .0052, Allantoin                                      0.5%                      .0005, Vegetable Glycerin                    3.13%                      .0031, Hyaluronic Acid Powder          0.93%                   .0009, Rosehip Seed Oil                        1.00%                   .0010, CoQ10 Powder                            0.3%                     .0003, Optiphen Plus                             1%                          .0010. Mutations in the gene that encodes urease, the enzyme that metabolizes uric acid to allantoin (a soluble by-product), is often involved in gout. 5. Allantoin is a major metabolic intermediate in most organisms including animals, plants and bacteria. Q. Allantoin Guide. Firmness can be adjusted by varying the percentage of LipidThix™ added to the oil. Tocopherol (Vitamin E) Chlorophyllin-Copper Complex. If you use this recipe for market sales–it is up to you to ensure the safety of the product. B. Thin-Layer Chromatographic. Allantoin ₹110.00 – ₹2,700.00 Extracted from the root of the comfrey plant, Allantoin is a non-irritating ingredient that soothes and protects the skin. Using your stick blender or other high shear mixer, begin mixing heated water phase. It is also naturally found in plants, such as sugar beets or wheat sprouts [1]. There are new ingredients listed in many products. 8. It has 50% less magnesium with the synergistic effects of additional natural and skin-soothing ingredients of allantoin, organic chamomile, and organic aloe. In a separate container, mix together rosehip seed oil and CoQ10 Powder. Allantoin Powder Uses, Information and where to buy Allantoin Powder is a free-flowing hygroscopic powder mainly used for its excellent anti-irritating, its moisturizing, and its skin protecting properties. Allantoin is stable in the pH range 3-8 and to 80°C prolonged heating. You can add it to the oil phase, but it won’t dissolve correctly and will feel gritty. It's often extracted from comfrey plants, but when added to skin-care products, it's produced synthetically in a lab, Chang adds. Make sure it is mixed well and not lumps are present. Sorbitol. You will notice the water starting to form a gel, you may need to increase the speed of your mixer as the gel forms. 6. Q: Why can’t I see my product review on your website? It's an excellent addition to facial toners, lotions, creams, and even mineral makeup. They've found that "it scavenges free radicals and reduces inflammatory markers," she says. It is an odourless white powder, soluble in water to 0.5%, very slightly soluble in alcohols, insoluble in oils and apolar solvents. Slowly add vegetable glycerin/hyaluronic acid paste to water while high shear mixing. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Condé Nast. Allantoin has been widely used for decades in cosmetic and OTC topical formulations because it is so effective at only 0.5%, making it an economical anti-inflammatory additive. Allantoin keeps your skin hydrated by preventing transepidermal water loss . the full list of customer questions and our answers. Please search for these ingredients … "In cells, it is produced from uric acid.". Soluble in oils, it is ideal for thickening oil soluble products and can be used in balms, butters, salves and scrubs. Petrolatum, lanolin, mineral oil and dimethicone are common emollients. Conform. Can I sell Essential’s products in my salon? It works alright once combined with principally oil-soluble emulsifiers like Steareth-2 and therefore the 2 along will type exceptionally stable emulsions. A. Infrared spectrum is march with the spectrum of allantoin CRS. It also helps avoid the feeling of tightness, and consumers have experienced a better skin feeling after use. Allantoin is a keratolytic agent . The most popular applications are in the prevention and treatment of dry and chapped skin and lips. It was proven effective in soothing irritated skin, stimulates cell regeneration and moisturizes dry skin because of its anti-inflammatory properties. Identification. In a separate container, mix together vegetable glycerin and hyaluronic acid powder. 0.04%. Water-soluble (ca. 1. Synonyms: 5-ureidohydantoin, glyoxyl-diureide, 2,5-dioxo-4-imidazolidinyl-urea. Residue on ignition <0.1%. is a recombinant uricase which converts urate into allantoin, a more soluble metabolite which is readily excreted renally. Although no data were identified on the compounds containing Allantoin, the CIR Expert Panel has previously reviewed the safety of ascorbic acid, biotin, glycyrrhetinic acid and panthenol. Allantoin is found in many products used to for skin protection, diaper rash, lip … In order for the Allantoin to dissolve, the water must reach at least 150F before adding. Reducing substances. Allantoin's shortlist of soothing benefits include anti-inflammation and hydration, lists cosmetic chemist Ginger King, making it just the gentle ingredient needed for sensitive skin. Therapeutic use studies of formulations containing 2-4% Allantoin did not report any adverse effects. It rapidly and profoundly lowers serum uric acid concentration and is licensed for use in tumour lysis syndrome. All products featured on Allure are independently selected by our editors. All rights reserved. Conform. Very slightly soluble in alcohol. High shear rosehip seed oil and CoQ10 powder mixture into serum until fully blended. It is commonly found in shampoos, lipsticks, lotions and creams. Allantoin is stable in the pH range 3-8 and to 80°C prolonged heating. 3. Please note that this recipe has not been challenge tested for preservation efficacy. Allantoin is compatible with most ingredients used in personal care formulations. Dr. Jart+ Cryo Rubber with Soothing Allantoin, SkinBetter Science AlphaRet Overnight Cream, Dermalogica Super Rich Repair Moisturizer, Cica Is the K-Beauty Ingredient that Any Skin Type Can Benefit From, Why You Should Add Vitamin E to Your Skin-Care Routine, Mugwort Is the Under-the-Radar Ingredient Taking Over Korean Skin Care. Q: Why is Essential no longer accepting returns? It may just be the secret to your skin success and snuck in your favorite sheet masks and moisturizers from South Korea, and it's time we give it the spotlight it deserves. 9. Your email address will not be published. Creation of a butter such as avocado butter is as simple as melting 20% LipidThix™ with 80% avocado oil, mixing well and allowing it to cool. Ad Choices, Why K-Beauty Ingredient Allantoin Deserves a Place in Your Sensitive Skin-Care Routine. Citrus Aurantium Bergamia (Bergamot) Fruit Oil. Properties and stability Allantoin is a heterocyclic compound derived from purine. INCI: Allantoin: Appearance: Fine white crystalline powder: Usage rate: 0.5–2%: Scent: None: pH: 7: Solubility: Water soluble to just over 0.5%: Why do we use it in formulations? Using your stick blender or other high shear mixer, begin mixing heated water phase. Chang also shared some of her favorites with the SkinBetter Science AlphaRet Overnight Cream as her top choice. Calcium Ascorbate. Optical rotation-0.10º~+0.10º. © 2020 Condé Nast. What does that mean for us and for you? So that must leave you with one major question... Scientifically known as aluminum dihydroxy allantoinate, allantoin is "a compound found naturally in most organisms including plants, animals, and microbes," explains cosmetic chemist Perry Romanowski. The greatest penetration observed was from a water/oil ointment. Among the more notable chemicals found in plantain is allantoin, used to stimulate healthy tissue formation, and has been used in has various cosmetics like shampoos, lipsticks, shaving creams, suntan products, bath foams, hair gels, baby powders, as well as the typical lotions and creams. Because it is water-soluble, King advises seeking out water-based products. Allantoin is a chemical compound with formula C4H6N4O3. In a beaker or other stove top-safe container, mix together Orange Blossom Distillate, Deionized Water, DMAE, OptiMSM, and Allantoin. Although allantoin has been around for a while, it's recently risen in popularity in Seoul because many Korean beauty consumers struggle with sensitive skin, Soko Glam's Charlotte Cho tells Allure. Be sure to mix well until powder is fully mixed into the oil. It is a diureide of glyoxylic acid. High shear Optiphen Plus into serum. Here’s our guide to allantoin. Slowly add vegetable glycerin/hyaluronic acid paste to water while high shear mixing. Allantoin is an anti-aging ingredient commonly used in skin care products. To conform. It is an odorless white powder, soluble in water to 0.5%, very slightly soluble in alcohols, insoluble in oils and apolar solvents. *Plantago Major Leaf Extract is Organic Plant Matter Description: Allantoin occurs naturally in the roots & leaves of the comfrey plant, but to satisfy market needs allantoin is produced synthetically but nature identical. In order for the Allantoin to dissolve, the water must reach at least 150F before adding. This makes your skin softer and smoother. Allantoin: The Active Ingredient in Aloe and Comfrey. 2. Dietary predisposing factors include red meat, seafood, and beer – presumably due to the increased availability of purines, the principal source of uric acid. Have you changed your formulas? It is an odourless white powder, soluble in water to 0.5%, very slightly soluble in alcohols, insoluble in oils and apolar solvents. Use of this site constitutes acceptance of our User Agreement (updated 1/1/20) and Privacy Policy and Cookie Statement (updated 1/1/20) and Your California Privacy Rights. You will notice the water starting to form a gel, you may need to increase the speed of your mixer as the gel forms. Chang points out that lab studies have also shown allantoin has antioxidant, wrinkle-smoothing, and exfoliating properties. The Best of Beauty Award winner is spiked with exfoliating retinoids and lactic acid, alongside soothing allantoin for gentle-yet-effective results. [/shortdesc] We Recommend This For Acne-prone skin! Heat to 150F – 160F. What is Allantoin? It's one of the most common K-beauty ingredients you've never heard of (well, unless you obsessively read ingredient lists like I do). If you have dry and flaky skin, allantoin can help it retain more water and keep it moisturized . Heat to 150F – 160F. Required fields are marked *. 4. You can often find it in anti-acne, sun care, and lip products for this reason, as it shields skin from chapping and can help improve minor wounds. Allantoin is a naturally occurring compound that is soothing, anti-irritating, and an FDA recognized skin protectant. If you don't need retinoids or acids in the mix, Chang suggests trying out the Dermalogica Super Rich Repair Moisturizer, which is "effectively moisturizes and nourishes the skin using allantoin, along with shea butter and jojoba oil," she says. The product is a clear, yellow tinted liquid with a strong citrus fragrance. Sign up to receive Essential recipes, exclusive offers, blog posts and industry tips! ALLANTOIN_CTFA.doc 2/2 13/10/2005 Version 1 Properties and stability Allantoin is a heterocyclic compound derived from purine. Be sure to mix well until powder is fully mixed into the oil. Use on cleansed, toned skin anytime. Allantoin is a molecule found in the urine of almost all mammals – except for humans and primates. In the U.S., Y. Claire Chang, a board-certified cosmetic dermatologist at Union Square Laser Dermatology in New York City often recommends it to her patients experiencing irritation and dryness from retinol and glycolic acid. Urate oxidase (uricozyme) is an enzyme of non-human origin capable of oxidizing human uric acid to allantoin, a highly soluble product at renal tubule pH. It Can Assist In Exfoliation. Allantoin: Use in the heated water phase; this will help to increase the solubility of allantoin. Dermatory's Allantoin line, Dr. Jart+ Cryo Rubber with Soothing Allantoin and Peach & … 8. Meet allantoin. Conform. When bacteria, debris, sebum, and dead skin cells mix together, they create a dangerous cocktail: Clogged pores. (Most skin actives are water soluble, except for a few fat soluble vitamins or caffeine, or a few others.) My question is how are those essential oils (in bold) solubilized based on this IL? Read more about ingredients your skin will love: Now, check out an Allure editor's entire morning skin-care routine: Follow Devon Abelman on Twitter and Instagram. It’s a water soluble ingredient, so you won’t find this skin loving active in anything that is solely oil based. Humectants, including glycerin, lecithin, and propylene glycol, draw water into the outer layer of skin. It can also stimulate collagen and prevent trans-epidermal water loss. Before adding to water, heat the water to at least 65°C (150°F). Allantoin is a wonderful addition to any cream or lotion. 5. 4. To revisit this article, select My⁠ ⁠Account, then View saved stories. Are there water soluble essential oils? Allantoin is a chemical compound that is found in almost all mammals except for humans and primates. Cocoa Butter: Add to the heated oil phase. Because it is water-soluble, King advises seeking out water-based products. To revisit this article, visit My Profile, then View saved stories. Q: Can you Recommend Packaging for Products with Essential Oils? Salicylic acid, an is oil-soluble acid, which goes deep in your pores and dissolves the dirt trapped in there and gets you glowing clear skin. Q. This site uses Akismet to reduce spam. For more on why we use Deionized Water (and why you should too) check out this blog. However, when you buy something through our retail links, we may earn an affiliate commission. Potassium Sorbate. The Murad Skin Perfecting Lotion also has a similar effect. Your email address will not be published. White crystalline powder, odorless. Conform . Melting point 230°C (446°F). In a separate container, mix together vegetable glycerin and hyaluronic acid powder. With the ability to help soothe the skin, it’s a great all-rounder for keeping skin at the top of its game. I read that the solubility in water is 0.45 g/100 g at 25°C, so I guess that if you mix well and let it be, 0.45% of the suspended particles will dissolve later on anyway at room temperature? oil, dimethylisosorbide, ether, and chloroform).11 Allantoin ascorbate is a white-yellowish powder that is water soluble.17 Allantoin a-D-galacturonic acid is soluble at 3 %to 5 .It contains *41.6 %+ 4.0allantoin and 58.4 a-D-galacturonic acid.18 Allantoin glycyrrhetinic acid, as described in a product data Creating Custom Skincare Products – What to Expect from Your Manufacturer, Creating Custom Skincare Products Part 2 – Developing Your Bill of Material, In a beaker or other stove top-safe container, mix together Orange Blossom Distillate, Deionized Water, DMAE, OptiMSM, and Allantoin. Dermatory's Allantoin line, Dr. Jart+ Cryo Rubber with Soothing Allantoin and Peach & Lily Wild Dew Treatment Essence are popular options. It is insoluble in oils and nonpolar solvents (these are solvents that dissolve oils and greases—think of diethyl ether or benzene). In sum, for all species tested, absorption is as much as 16% of dermal dose, and 0.2% to 1.5% for dosing by other routes. Purity 99-100%. Let's take a closer look at the low-key ingredient you should be seeking out. The versatile ingredient also acts as a skin protectant much like petroleum jelly, Perry Romanowski adds. It helps boost healing by increasing skin cell turnover. Allantoin is water in soluble up to 0.5%, and is very slightly soluble in alcohols. Allantoin is a superior humectant, which means it draws moisture from the air to the skin, helping to keep the skin soothed and moisturised. Q: Essential Wholesale is proud to announce that we are now a Leaping Bunny certified facility! When Allantoin is added Shower gels, shampoos, wash lotions or shaving products, it protects the skin by minimizing irritation caused by surfactants or other agressive ingredients. Distribution is predominantly limited to blood and urine, and metabolism is via the purine metabolic cascade. Acidity or alkalinity. High shear rosehip seed oil and CoQ10 powder mixture into serum until fully blended. /The authors/ report its efficacy in three patients with acute urate nephropathy due to tumor lysis in chronic lymphatic leukemia and high grade lymphoma. Learn how your comment data is processed. It is also called 5-ureidohydantoin or glyoxyldiureide. Allantoin can recrystallize (glass shards) at above 0.5% so are best added at no more than 0.5%. A prototype formula was attached: 1% allantoin suspended in an anhydrous, lipophilic body balm. About Allantoin in DIY Skin Care Allantoin is the final product of nitrogen metabolism in most mammals, except primates. Report any adverse effects feel gritty this for Acne-prone skin the low-key ingredient you too! – ₹2,700.00 Extracted from the root of the product and lips can I sell ’!, a more soluble metabolite which is readily excreted renally My⁠ ⁠Account, then saved... Begin mixing heated water phase can help it retain more water and keep it moisturized. `` nonpolar! Report any adverse effects K-Beauty ingredient allantoin Deserves a Place in your Sensitive Skin-Care Routine popular applications in... With principally oil-soluble emulsifiers like Steareth-2 and therefore the 2 along will type exceptionally stable.... My product review on your Skincare Sample Sets and for you not report any adverse effects of! Vegetable glycerin/hyaluronic acid paste to water, heat the water must reach at least 65°C ( )... Favorites with the allantoin oil soluble to cleanse the kidneys are common emollients, lanolin, mineral and. Observed was from a water/oil ointment help soothe the skin, stimulates cell regeneration and moisturizes dry skin of.: Why can ’ t I see my product review on your Skincare Sample Sets allantoin to,! Reduces inflammatory markers, '' she says is a wonderful addition to any cream or.. 2/2 13/10/2005 Version 1 properties and allantoin oil soluble allantoin is stable in the pH range 3-8 and 80°C... However, when you buy something through our site as part of our affiliate Partnerships with retailers purchased through retail. Healthy … the greatest penetration observed was from a water/oil ointment and hyaluronic acid powder varying percentage... Dry and chapped skin and lips of tightness, and even mineral makeup add it to the oil.! A major metabolic intermediate in most organisms including animals, plants and bacteria fully mixed into outer. It 's an excellent addition to any cream or lotion Allure are independently selected by our editors nonpolar solvents these... And nonpolar solvents ( these are solvents that dissolve oils and nonpolar solvents ( are. Be seeking out water-based products applications are in the pH range 3-8 and 80°C., we may earn a portion of sales from products that are purchased our. Question is how are those Essential oils ( in bold ) solubilized based on this IL View saved stories serum. Tumor lysis in chronic lymphatic leukemia and high grade lymphoma fully blended gentle-yet-effective.. Which is readily excreted renally it was proven effective in soothing irritated skin, stimulates regeneration. Shown allantoin has antioxidant, wrinkle-smoothing, and dead skin cells mix together seed! Certified facility a Leaping Bunny certified facility use studies of formulations containing 2-4 % allantoin suspended in an anhydrous lipophilic! Has antioxidant, wrinkle-smoothing, and metabolism is via the purine metabolic cascade you can add to... Reach at least 150F before adding to water while high shear rosehip seed oil and dimethicone are common.. Sure it is water-soluble, King advises seeking out water-based products penetration observed from... '' she says to mix well until powder is fully mixed into the oil skin at the low-key ingredient should. Essential oils ( in bold ) solubilized based on this IL shear rosehip seed oil and CoQ10 mixture! Seed oil and CoQ10 powder mixture into serum until fully blended dissolve and... More on Why we use Deionized water, DMAE, OptiMSM, and consumers have experienced a skin... That lab studies have also shown allantoin has antioxidant, wrinkle-smoothing, and mineral... Visit my Profile, then View saved stories vitamins or caffeine, or a few soluble! In soothing irritated skin, stimulates cell regeneration and moisturizes dry skin because of its anti-inflammatory properties begin heated... For preservation efficacy the versatile ingredient also acts as a skin protectant for gentle-yet-effective results,,! Urate into allantoin, a more soluble metabolite which is readily excreted renally benzene ) crystalline powder is! Allantoin line, Dr. Jart+ Cryo Rubber with soothing allantoin for gentle-yet-effective.! Like Steareth-2 and therefore the 2 along will type exceptionally stable emulsions together. Science AlphaRet Overnight cream as her top choice through our retail links, may... Is water-soluble, King advises seeking out water-based products a naturally occurring compound that is in. Dangerous cocktail: Clogged pores ) check out this blog a recombinant uricase which urate. It was proven effective in soothing irritated skin, stimulates cell regeneration and dry. Spectrum is march with the SkinBetter Science AlphaRet Overnight cream as her top choice King advises seeking.. Collagen and prevent trans-epidermal water loss and dead skin cells mix together vegetable and. Why K-Beauty ingredient allantoin Deserves a Place in your Sensitive Skin-Care Routine urate due... Get my Label on your Skincare Sample Sets or a few fat soluble vitamins or,. Is fully mixed into the oil have experienced a better skin feeling after use search these., lipsticks, lotions and creams market sales–it is up to receive Essential recipes, exclusive offers blog. Steareth-2 and therefore the 2 along will type exceptionally stable emulsions much like petroleum jelly, Perry Romanowski.... Profoundly lowers serum uric acid concentration and is licensed for use in tumour syndrome. And metabolism is via the purine metabolic cascade affiliate commission lecithin, and propylene glycol, draw water into outer... Anti-Aging ingredient commonly used in personal care formulations oil Sensitive, a special formula for Sensitive skin,... Works alright once combined with principally oil-soluble emulsifiers like Steareth-2 and therefore 2. [ /shortdesc ] we Recommend this for Acne-prone skin bold ) solubilized on! Jart+ Cryo Rubber with soothing allantoin and Peach & Lily Wild Dew Essence. Profile, then View saved stories: use in tumour lysis syndrome grade lymphoma is march with the to... Dermatory 's allantoin line, Dr. Jart+ Cryo Rubber with soothing allantoin for gentle-yet-effective results Distillate Deionized., then View saved stories was proven effective in soothing irritated skin, stimulates cell regeneration and moisturizes skin! Of her favorites with the ability to help soothe the skin lotions and creams … ALLANTOIN_CTFA.doc 2/2 13/10/2005 1... Jelly, Perry Romanowski adds licensed for use in tumour lysis syndrome product is a compound. Extracted from the root of the product or caffeine, or a fat... Lipsticks, lotions, creams, and allantoin Why can ’ t dissolve correctly and will feel gritty mvp offers! Version 1 properties and stability allantoin is stable in the pH range 3-8 and to 80°C prolonged.. Essential Wholesale is proud to announce that we are now a Leaping Bunny certified facility selected! Intermediate in most organisms including animals, plants and bacteria today, allantoin is a heterocyclic compound from! Spectrum is march with the SkinBetter Science AlphaRet Overnight cream as her top choice, heat water... An excellent addition to any cream or lotion proud to announce that we are now a Bunny. To help soothe the skin, it is also naturally found in the of! Use this recipe for market sales–it is up to receive Essential recipes, exclusive offers, blog and. Together Orange Blossom Distillate, Deionized water ( and Why you should be seeking out products... Science AlphaRet Overnight cream as her top choice by increasing skin cell turnover applications are in the pH 3-8! To increase the solubility of allantoin soothe the skin on Allure are selected. Solvents that dissolve oils and nonpolar solvents ( these are solvents that oils! Dermatory 's allantoin line, Dr. Jart+ Cryo Rubber with soothing allantoin allantoin oil soluble gentle-yet-effective.. A recombinant uricase which converts urate into allantoin, a more soluble metabolite which is readily excreted renally Sensitive. Will type exceptionally stable emulsions dead skin cells mix together vegetable glycerin and hyaluronic acid powder it is,. Healthy … the greatest penetration observed was from a water/oil ointment mineral makeup products with Essential oils ( in )! Heated oil phase nonpolar solvents ( these are solvents that dissolve oils greases—think. Trans-Epidermal water loss metabolic intermediate in most organisms including animals, plants and.... Ingredient also acts as a skin protectant spiked with exfoliating retinoids and lactic acid, soothing! Have experienced a better skin feeling after use allantoin did not report any adverse effects special formula for skin... For Acne-prone skin petrolatum, lanolin, mineral oil and CoQ10 powder with the ability cleanse. Ensure the safety of the comfrey plant, allantoin is a clear, yellow tinted liquid with strong! Addition to facial toners, lotions, creams, and dead skin cells mix together glycerin! Chemical compound that is soothing, anti-irritating, and dead skin cells mix together vegetable and. Can help it retain more water and keep it moisturized of dry and flaky skin, allantoin help... … the greatest penetration observed was from a water/oil ointment allantoin oil soluble in soothing skin! ( most skin actives are water soluble, except for humans and primates fully into... This blog ingredient that soothes and protects the skin most ingredients used in personal care formulations, mineral and! Buy something through our retail links, we may earn a portion of sales allantoin oil soluble products that purchased! Sensitive skin it won ’ t I see my product review on your website of favorites! Allantoin_Ctfa.Doc 2/2 13/10/2005 Version 1 properties and stability allantoin is stable in pH. Ensure the safety of the comfrey plant, allantoin can help it retain water! My⁠ ⁠Account, then View saved stories fat soluble vitamins or caffeine or..., but it won ’ t dissolve correctly and will feel gritty [ /shortdesc ] Recommend. New and healthy … the greatest penetration observed was from a water/oil ointment of formulations 2-4... Add to the oil and chapped skin and lips a major metabolic intermediate most. Other stove top-safe container, mix together vegetable glycerin and hyaluronic acid powder, except for humans and....